Research Projects

The Clayton Foundation for Research and its supporting entities currently conduct and fund medical research programs in the following areas:


Cancer

  • Targeted immuno- therapeutics
  • Engineered proteases
  • Next generation anti-mitotic drugs
  • Fc engineered aglycosylated antibodies
  • Immuno-oncology: targeting novel-intrinsic PD Pathways
  • Novel therapeutic strategies for liver cancer

CNS, Opthalmology

  • Stem cell therapy for Parkinson’s Disease
  • Modulation of brain stress in neurological diseases
  • Genetic disease models for neurological diseases
  • Gene therapy and peptide therapeutics for AMD
  • Early detection and treatment of glaucoma
  • Electroceutical therapies

Metabolic Diseases

  • Microbiome in obesity and diabetes
  • Molecular switches in glucose control
  • Mitotic checkpoint regulators in insulin signaling

Infectious Diseases

  • Vaccines and diagnostics for Ehrlichioses
  • Drug discovery program to host-based antiviral targets

Autoimmune, Inflammation

  • Engineered proteases
  • Fc engineering of aglycosylated antibodies

Cardiology

  • OCT-TPL diagnostics of human vascular plaques to predict heart attacks and strokes