The Clayton Foundation for Research and its supporting entities currently conduct and fund medical research programs in the following areas:
Cancer
- Targeted immuno- therapeutics
- Engineered proteases
- Next generation anti-mitotic drugs
- Fc engineered aglycosylated antibodies
- Immuno-oncology: targeting novel-intrinsic PD Pathways
- Novel therapeutic strategies for liver cancer
CNS, Opthalmology
- Stem cell therapy for Parkinson’s Disease
- Modulation of brain stress in neurological diseases
- Genetic disease models for neurological diseases
- Gene therapy and peptide therapeutics for AMD
- Early detection and treatment of glaucoma
- Electroceutical therapies
Metabolic Diseases
- Microbiome in obesity and diabetes
- Molecular switches in glucose control
- Mitotic checkpoint regulators in insulin signaling
Infectious Diseases
- Vaccines and diagnostics for Ehrlichioses
- Drug discovery program to host-based antiviral targets
Autoimmune, Inflammation
- Engineered proteases
- Fc engineering of aglycosylated antibodies
Cardiology
- OCT-TPL diagnostics of human vascular plaques to predict heart attacks and strokes